Related Experiment Video
Updated: Apr 21, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
Excess granulation tissue and hair loss following acitretin
Francesca Gaudiello1, Massimiliano Scalvenzi1, Lucia Gallo1
1Dipartimento di Patologia Sistematica, Sezione di Dermatologia clinica, allergologica e venereologica, Università di Napoli Federico II, Napoli, Italy.
Abstract:
Retinoids are routinely used in dermatology for various clinical entities including acne vulgaris, rosacea, hypertrophic scars, strie distensae, psoriasis, disorders of dyskeratinization, cancer prevention and other chronic hyperkeratotic disorders. Oral acitretin therapy is effective in the treatment of psoriasis normalizing cellular differentiation and maturation but clinical side-effects are reported. We describe the occurrence of excess granulation tissue in the nails sulcus and noncicatricial universal alopecia in a psoriatic patient receiving oral acitretin.
Related Concept Videos
Accessory Structures of the Skin: Hair Growth and Types
Multipotency and Niche of Bulge Stem Cell
Acne Infection
Accessory Structures of the Skin: Sebaceous Glands
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Accessory Structures of the Skin: Hair and Hair Follicles
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
Reticular Dermis
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

