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cAMP levels in monocytes of heroin addicts
J L Castrillón1, J L Arellano, J D Palomo
1Departamento de Patologia General, Hospital Clinico Universitario, Salamanca Hispania.
Klinische Wochenschrift
|February 15, 1989
Abstract:
Intravenous heroin addicts have a high intracellular cAMP level in relation to control monocytes. Incubation in vitro with ascorbic acid normalizes the cellular content of cAMP. We discuss the role of cAMP in the pathogenesis of defective monocyte chemotaxis in intravenous heroin addicts.