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Functional capacity of patients with pacemaker due to isolated congenital atrioventricular block

Roberto Márcio de Oliveira Júnior1, Kátia Regina da Silva1, Tatiana Satie Kawauchi1

  • 1Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.

Arquivos Brasileiros De Cardiologia
|November 13, 2014
PubMed

Insights

Children and young adults with isolated congenital atrioventricular block (CAVB) and chronic right ventricular pacing show good functional capacity. This capacity did not correlate with predictors of ventricular remodeling.

Area of Science:

  • Cardiology
  • Pediatrics
  • Electrophysiology

Background:

  • Isolated congenital atrioventricular block (CAVB) is a rare condition with varied clinical outcomes.
  • Ventricular remodeling affects approximately 10% of patients post-pacemaker (PM) implantation.

Purpose of the Study:

  • To assess functional capacity in children and young adults with isolated CAVB and chronic right ventricular (RV) pacing.
  • To evaluate the correlation between functional capacity and predictors of ventricular remodeling.

Main Methods:

  • Cross-sectional study of 61 patients with isolated CAVB and RV pacing for over a year.
  • Clinical and echocardiographic evaluations were performed.
  • Functional capacity assessed via the six-minute walk test; statistical analysis included Chi-square, Fisher's exact test, and Pearson correlation.

Main Results:

  • The study included 61 individuals (67.2% female, aged 7-41 years) with a mean pacing duration of 13.5 years.
  • 97.9% ventricular pacing, paced QRS duration of 153.7 ms; 95.1% were asymptomatic.
  • Mean walk distance was 546.9 meters, strongly correlated with predicted distance (r=0.907, p=0.001), but not with ventricular remodeling risk factors.

Conclusions:

  • Patients with isolated CAVB and chronic RV pacing demonstrate satisfactory functional capacity.
  • Functional capacity in this cohort did not correlate with identified risk factors for ventricular remodeling.
Abstract

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