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Structural Protein Function

Structural Protein Function

Structural Protein Function

Structural Protein Function

Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to...

Genome Annotation and Assembly

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.

Protein Networks

Protein Networks

Protein Networks

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...

Protein Organization

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence....

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Related Experiment Video

Updated: Apr 21, 2026

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

Introduction to structural bioinformatics.

Qin Xu¹, Hao Dai, Tangzhen Zhao

¹State Key Laboratory of Microbial Metabolism, College of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.

Advances in Experimental Medicine and Biology

|November 13, 2014

Summary

This summary is machine-generated.

This book explores structural bioinformatics, a rapidly advancing interdisciplinary field. It covers methods, protein structure prediction, molecular interactions, and applications in drug design.

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A Protocol for Computer-Based Protein Structure and Function Prediction

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A Protocol for Computer-Based Protein Structure and Function Prediction

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

Area of Science:

Structural bioinformatics is a rapidly advancing interdisciplinary scientific field.

Background:

Recent years have seen significant progress in structural bioinformatics.
The interdisciplinary nature of structural bioinformatics makes strict categorization challenging.

Purpose of the Study:

This book provides an overview of structural bioinformatics concepts.
It details the book's contents, organized by application areas.

Main Methods:

Chapters are organized by application: fundamental methods, tertiary structure prediction, folding mechanisms, macromolecule-ligand interactions, structure-based functional analysis, and drug design applications.

Main Results:

The book covers key areas within structural bioinformatics.
It highlights the diverse applications of structural bioinformatics.

Conclusions:

Structural bioinformatics is a dynamic field with broad applications.
This book serves as a comprehensive guide to its various facets.