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Hypertension Subtypes among Hypertensive Patients in Ibadan

Abiodun M Adeoye1, Adewole Adebiyi1, Bamidele O Tayo2

  • 1Department of Medicine, University of Ibadan, Ibadan, Nigeria.

International Journal of Hypertension
|November 13, 2014
PubMed

Insights

In Nigerian hypertensive patients, systolic-diastolic hypertension was most common. Gender and obesity significantly influenced hypertension subtypes, suggesting a need for subtype characterization in genetic studies.

Area of Science:

  • Cardiology
  • Genetics
  • Public Health

Background:

  • Hypertension subtypes are linked to cardiovascular risks and potential genetic factors.
  • Accurate hypertension subtyping is crucial for understanding genetic contributions to its development.
  • This study investigates hypertension subtypes in South-Western Nigerian patients.

Purpose of the Study:

  • To characterize and report the prevalence of different hypertension subtypes in a Nigerian population.
  • To explore the influence of gender and obesity on hypertension subtype distribution.

Main Methods:

  • A cross-sectional study of 1858 hypertensive individuals (≥18 years) in Ibadan, Nigeria.
  • Hypertension classified using JNC VII criteria into four subtypes: controlled hypertension (CH), isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH), and systolic-diastolic hypertension (SDH).
  • Statistical analysis to determine prevalence and associations with gender and obesity.

Main Results:

  • Systolic-diastolic hypertension (SDH) was the most prevalent subtype.
  • SDH and isolated diastolic hypertension (IDH) were more common in females, while isolated systolic hypertension (ISH) was more prevalent in males.
  • Obesity was more common in females, and SDH was prevalent in the obese group.

Conclusions:

  • Gender and obesity significantly impact the distribution of hypertension subtypes in this population.
  • Subtyping hypertension is essential for identifying novel genetic variants in hypertension etiology.
  • Further large-scale, multi-ethnic studies are recommended to validate these findings.

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