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Updated: Apr 21, 2026
Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres
Published on: February 2, 2015
Reverse magnetic resonance signal from intraocular hemorrhage
Leanne T Labriola1, Carol L Shields, Carl J Danzig
1From the *Oncology Service, Wills Eye Hospital, and the †Department of Neuroradiology, Thomas Jefferson University, Philadelphia, Pennsylvania.
Purpose:
To report the effect of massive intraocular hemorrhage on magnetic resonance imaging signal.
Methods:
Case report.
Results:
A 34-year-old power weightlifter developed sudden, nontraumatic loss of vision to no light perception in his right eye. Magnetic resonance imaging (MRI) revealed homogeneous bright signal on T1-weighted images and dark signal on T2-weighted images, opposite the signal of his normal left eye. These findings were suggestive of subacute massive intraocular hemorrhage. The patient elected enucleation for the blind, painful eye. The diagnosis made by MRI signal interpretation was confirmed by subsequent histopathology analysis.
Conclusion:
Based on hemoglobin degradation products, MRI can assist in judging the stage of blood breakdown and diagnosing intraocular pathology.
