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Related Experiment Video

Updated: Apr 21, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Bilateral choroidal osteomas with polypoidal choroidal vasculopathy.

Howard F Fine1, Daniela C Ferrara, I-Van Ho

  • 1From the Vitreous, Retina, Macula Consultants of New York, and the LuEsther T. Mertz Retina Research Laboratory, Manhattan Eye, Ear, and Throat Hospital, New York, New York.

Retinal Cases & Brief Reports
|November 13, 2014
PubMed
Summary
This summary is machine-generated.

This case report describes bilateral polypoidal choroidal neovascularization (PCV) in a patient with choroidal osteomas. This association may offer a better prognosis than classic choroidal neovascularization (CNV).

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Area of Science:

  • Ophthalmology
  • Oncology

Background:

  • Choroidal osteomas are benign tumors.
  • Visual loss is often due to subretinal neovascular membranes.
  • Neovascularization in osteomas is typically classic choroidal neovascularization (CNV).

Purpose of the Study:

  • To report a rare case of bilateral polypoidal choroidal neovascularization (PCV) associated with bilateral choroidal osteomas.
  • To discuss the clinical, angiographic, and optical coherence tomographic findings.
  • To evaluate the potential prognosis of this association.

Main Methods:

  • Interventional case report.
  • Clinical examination.
  • Indocyanine green angiography.
  • Optical coherence tomography.
  • Photodynamic therapy.

Main Results:

  • A 55-year-old Japanese woman presented with bilateral choroidal osteomas and bilateral PCV.
  • Subretinal hemorrhage in the macula due to PCV was successfully treated with photodynamic therapy.
  • This represents a previously undescribed variant of vasogenesis in association with choroidal osteomas.

Conclusions:

  • The association of choroidal osteoma with PCV may have a better prognosis than with classic CNV.
  • Indocyanine green angiography is crucial for characterizing neovascularization in these cases.