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Updated: Apr 21, 2026
The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION
Published on: November 20, 2016
Optic nerve macroaneurysms as the initial presentation of idiopathic retinal vasculitis, aneurysms, and
Ketan Laud1, Wael El-Haig, Lawrence A Yannuzzi
1From the *Vitreous, Retina, Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York; and the †Department of Ophthalmology, Zagazig University, Zagazig, Egypt.
Purpose:
To report a case of idiopathic retinal vasculitis, aneurysms, and retinitis (IRVAN) with macroaneurysms confined to the optic disk.
Methods:
A patient with IRVAN was examined with biomicroscopy and fluorescein angiography.
Results:
IRVAN typically presents with macroaneurysms along the first- and second-order arterioles. Our patient presented with peripapillary lipid exudation and macroaneurysms limited to the optic nerve. The macroaneurysms were best appreciated with fluorescein angiography.
Conclusions:
This case represents an atypical presentation of a rare but well documented retinal vascular disorder. It is important to recognize the earliest possible manifestations of IRVAN to establish an accurate diagnosis because it may be mistaken for a wide array of retinal vascular and optic nerve disorders.
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