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Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Hypercoagulable state in a patient with a retinal vein occlusion
Apkarian O Alexandra1, Kimberly A Drenser
1From the Associated Retinal Consultants and William Beaumont Hospital, Royal Oak, Michigan.
This case report highlights unusual hypercoagulability findings in a patient with retinal vein occlusion. Investigating hypercoagulability is crucial for preventing future thrombotic events in similar cases.
Area of Science:
- Ophthalmology
- Hematology
Background:
- Retinal vein occlusion (RVO) can be linked to hypercoagulable states.
- Investigating underlying causes is essential for patient management.
Purpose of the Study:
- To report unique hypercoagulability findings in an RVO patient.
- To emphasize the need for hypercoagulability workup in similar RVO cases.
Main Methods:
- Retrospective case report.
- Patient evaluated over several months.
- Laboratory and platelet function tests performed.
Main Results:
- Decreased antithrombin III activity identified.
- Prothrombin mutation detected.
- Platelet evaluation consistent with sticky platelet syndrome.
Conclusions:
- Hypercoagulability should be considered in RVO patients, especially those outside the typical young demographic.
- Prompt investigation can lead to intervention and prevention of thrombotic events.
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