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Updated: Apr 21, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
3d spectral optical coherence tomography documentation of a retinal vein occlusion associated with a pigment
Shantan Reddy1, Hideki Koizumi, Rob Peralta
1From the *Department of Ophthalmology, LuEsther T. Mertz Retinal Research Center of Manhattan Eye, Ear & Throat Hospital and New York University School of Medicine; and †Vitreous-Retina-Macula Consultants of New York, New York.
Purpose:
To describe a case of a pigment epithelial detachment (PED) that likely led to a branch retinal vein occlusion (BRVO).
Methods:
Color photography, fluorescein angiography, and three-dimensional spectral optical coherence tomography (3D-spectral OCT) were performed.
Results:
Fluorescein angiography identified a PED at the site of a BRVO, and 3D-spectral OCT illustrated compression and distortion of the overlying retina at the location of the venous obstruction.
Conclusion:
It is well known that retinal arterial disease can compress an underlying vein and lead to a BRVO. A theoretically possible, but previously unrecognized cause of a BRVO is compression of an overlying vein by an underlying PED. Our case reminds us to continue to explore local anatomical factors in addition to systemic factors in patients with venous occlusive disease.

