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Updated: Apr 21, 2026
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
COMBINED SCLERAL BUCKLING AND INTRAVITREAL PLASMIN INJECTION: A New Surgical Technique
Wei-Chi Wu1, Kimberly A Drenser, Michael T Trese
1From *Associated Retinal Consultants, PC, Royal Oak; †Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan; ‡Chang Gung University College of Medicine, Taoyuan, Taiwan; §William Beaumont Hospital, Royal Oak, Michigan; ¶Oakland University, Eye Research Institute, Rochester, Minnesota.
Purpose:
To report a new surgical technique for repair of rhegmatogenous retinal detachments in children.
Methods:
This study is an interventional case series. Combined scleral buckling and enzymatic vitrectomy by autologous plasmin was performed in three patients who presented with rhegmatogenous retinal detachment. Anatomic and functional outcomes as well as surgical complications were recorded.
Results:
Following combined surgery, all patients achieved retinal reattachment. Two patients had recordable and improved vision. None of the patients developed surgical complications after at least 21 months of follow-up.
Conclusion:
Combined scleral buckling and enzymatic vitrectomy achieves retinal reattachment and functional improvement in selected pediatric patients with rhegmatogenous retinal detachment who require scleral buckling and vitrectomy.
