Ocular rupture after accidental intraocular injection of bupivacaine

To report on the toxicity of bupivacaine that was accidentally injected into the eye.

Observational case report. Clinical and electroretinographic examinations of a 78-year-old woman who had an ocular rupture after an accidental intraocular injection of 0.25% bupivacaine.

The a- and b-waves of the electroretinographics were normal after the repair of the eye by vitrectomy. The corneal opacification and edema present after the rupture did not recover.

The exposure of the retina to 0.25% bupivacaine may not alter the function of the human retina.