Related Experiment Video
Updated: Apr 21, 2026
Reconstruct Human Retinoblastoma In Vitro
Published on: October 11, 2022
Simultaneous presentation of retinoblastoma and morning glory disk anomaly
Charles C Wykoff1, Sander R Dubovy, Julio C Barredo
1From the *Department of Ophthalmology, Bascom Palmer Eye Institute, and the †Department of Pediatric Hematology-Oncology, University of Miami Miller School of Medicine, Miami, Florida.
Purpose:
To describe a patient with retinoblastoma and morning glory disk anomaly (MGDA).
Method:
Observational case report.
Results:
A 7-month-old girl with bilateral retinoblastoma was found to have concurrent MGDA in the less involved eye. The more severely affected eye was enucleated due to progressive disease not amenable to aggressive systemic and local treatment; histologic analysis was performed.
Conclusion:
Prompt ocular examination of a pediatric patient should be performed in the presence of concerning findings such as leukokoria or strabismus. In addition, more than one ocular abnormality may coexist, such as retinoblastoma and MGDA, necessitating complete examination.
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