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Updated: Apr 21, 2026
Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
Retinal imaging with high-resolution high-speed optical coherence tomography in patients with nystagmus
Nicole Sinnema1, Aniki Rothova, Jan Stilma
1From the Department of Ophthalmology, FC Donders Institute of Ophthalmology, University Medical Center Utrecht, The Netherlands.
Purpose:
To compare the quality of retinal images in patients with nystagmus made by the Spectral Domain High-Resolution High-Speed Optical Coherence Tomography Copernicus (SD-OCT) and by the Time Domain Stratus Optical Coherence Tomography (Stratus-OCT).
Methods:
Three patients with a congenital horizontal nystagmus and various retinal features were tested with both the SD-OCT (Optopol, Rockmed, Poland) and the standard Stratus-OCT (Carl Zeiss Meditec, Dublin, CA).
Results:
Stratus-OCT exhibited "saw tooth" or waved images in all three patients with nystagmus and failed to discriminate the retinal layers. In contrast, the SD-OCT imaging gave clear representation of the retina with discrimination of intraretinal layers in all three patients.
Conclusion:
The high speed and resolution of SD-OCT resulted in discrimination of intraretinal layers in patients with nystagmus and indicates the potential of SD-OCT in diagnosing retinal disorders in patients with nystagmus.
