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Sclerochoroidal calcification in a patient with chronic hypercalcemia from undiagnosed parathyroid adenoma
John Y Choi1, Carlos Bianciotto, Jerry A Shields
1From *The National Retina Institute, Towson, Maryland; and †Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
Purpose:
To describe a case of sclerochoroidal calcification in a patient with hypercalcemia from undiagnosed parathyroid adenoma.
Methods:
A 66-year-old white woman was found to have asymptomatic bilateral yellow choroidal tumors characteristic of sclerochoroidal calcification. The calcified tumors were echogenic on ultrasonography.
Results:
Systemic evaluation disclosed hypercalcemia, and there was no abnormality of the parathyroid glands with hormone levels or nuclear medicine scans. After 4 years, the hypercalcemia persisted, prompting surgical exploration of the parathyroid glands that revealed an adenoma. After resection of the glands, the serum calcium reverted to normal.
Discussion:
Sclerochoroidal calcification can be associated with systemic hypercalcemia. A search for the cause is warranted, and in this case, a subclinical adenoma was the source of the hypercalcemia.
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