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Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Florid polyclonal lymphoid follicular hyperplasia presenting as leopard spot retinopathy
Jay B Futterman1, Lee M Jampol
1From the Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Purpose:
To describe a case of leopard spot retinopathy associated with a systemic polyclonal lymphoproliferative disorder. Other described causes of this clinical finding are reviewed.
Methods:
Case report. A previously healthy 50-year-old white male presented with decreased vision. Examination showed leopard spot retinopathy. He underwent ophthalmic and body imaging, laboratory workup, and biopsy of a lymph node and lacrimal gland.
Results:
The workup revealed a systemic polyclonal lymphoproliferative disorder which involved the orbit, lymph nodes, pancreas, kidney, and choroid.
Conclusion:
Leopard spot retinopathy is a clinical description associated with multiple etiologies. Choroidal infiltration related to a systemic polyclonal lymphoproliferative disorder is one cause.
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