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Updated: Apr 21, 2026
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Choroidal neovascular membrane after endoresection of choroidal melanoma
Daniela Suesskind1, Khakima Karim-Zade, Hakan Demirci
1From the *Center for Ophthalmology, Eberhard-Karls University of Tuebingen, Tuebingen, Germany; and †Department of Ophthalmology, Henry Ford Hospital, Detroit, Michigan.
Purpose:
The purpose of this study was to report two cases with choroidal melanoma who underwent endoresection and developed choroidal neovascular membrane (CNVM) during follow-up.
Methods:
An interventional case series.
Results:
A 62-year-old man with choroidal melanoma in his left eye was treated with endoresection with pars plana vitrectomy followed by radioactive ruthenium plaque radiotherapy. Thirteen months after the surgery, the patient developed a CNVM at the superior edge of the surgical excision site and was treated with argon laser photocoagulation. Twenty-eight months after laser photocoagulation, the patient was alive with no sign of CNVM recurrence. A 59-year-old man with choroidal melanoma in his left eye underwent endoresection with pars plana vitrectomy followed by radioactive ruthenium plaque radiotherapy. Twenty-one months later, he developed a CNVM, which was treated by photodynamic therapy. After 45 months of follow-up after photodynamic therapy, the patient had no sign of recurrent CNVM.
Conclusion:
Choroidal neovascular membrane is a rare complication after endoresection of choroidal melanoma. Being aware of this risk leads to early diagnosis and prompt treatment that can prevent deterioration of vision.
