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Related Experiment Video

Updated: Apr 21, 2026

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition
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Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

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Acute bilateral peripheral cone system dysfunction.

Takuji Kurimoto1, Mineo Kondo, Masashi Nishimura

  • 1From the *Department of Ophthalmology, Hyogo College of Medicine, Nishinomiya; and †Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Retinal Cases & Brief Reports
|November 13, 2014
PubMed
Summary
This summary is machine-generated.

This study details a rare case of acute peripheral vision loss in both eyes, revealing a specific dysfunction in the cone cells of the retina while sparing rod cells.

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Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Electrophysiology

Background:

  • Acute visual field loss can stem from various retinal pathologies.
  • Distinguishing between rod and cone dysfunction is crucial for diagnosis and management.

Purpose of the Study:

  • To present electrophysiological and psychophysical findings in a unique case of bilateral acute peripheral visual field loss.
  • To characterize the specific retinal dysfunction involved.

Main Methods:

  • Comprehensive ophthalmologic examination including fundus photography and fluorescein angiography.
  • Visual field testing (static perimetry) and electroretinography (full-field ERG and mfERG).
  • Psychophysical rod-cone perimetry was performed to assess rod and cone function separately.

Main Results:

  • Fundus examination and angiography were normal; visual acuity was preserved.
  • Perimetry showed distinct visual field defects in both eyes.
  • Full-field ERG revealed reduced cone responses with normal rod responses.
  • mfERGs indicated preserved central cone function but severely reduced peripheral cone responses.
  • Psychophysical testing confirmed peripheral cone impairment with normal rod sensitivity.

Conclusions:

  • The findings suggest an unusual retinopathy characterized by acute, bilateral peripheral cone system dysfunction.
  • The rod system remained unaffected, highlighting a specific pattern of retinal damage.
  • This case underscores the importance of detailed electrophysiological testing in diagnosing atypical visual field defects.