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Published on: October 27, 2014
Radiation maculopathy complicated by intraretinal neovascularization treated with intravitreal bevacizumab
Waheeda Rahman1, Nachiketa Acharya, Mandeep S Sagoo
1From the *Medical Retina Service, Moorfields Eye Hospital; and †UCL Institute of Ophthalmology, London, United Kingdom.
Purpose:
The purpose of this study was to describe a case of radiation maculopathy as a result of intraretinal neovascularization, treated with intravitreal bevacizumab.
Methods:
This is an interventional case report. A 51-year-old man was treated with radiotherapy and chemotherapy for nasopharyngeal carcinoma. He developed radiation maculopathy associated with intraretinal neovascularization in the left eye. He underwent a course of 3 intravitreal injections of bevacizumab (1.25 mg/0.05 mL).
Results:
The visual acuity in the left eye improved with complete closure of the intraretinal neovascularization and no recurrence 17 months after the last bevacizumab injection.
Conclusion:
This case of radiation-induced intraretinal neovascularization responded well to bevacizumab treatment. These lesions may respond more favorably if treated earlier.
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