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Updated: Apr 21, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Recurrent pseudomonas aeruginosa endophthalmitis
Seema Gupta1, Geoffrey G Emerson, Christina J Flaxel
1From the Casey Eye Institute, Oregon Health & Science University, Portland, Oregon. Dr. Emerson is now in private practice in St. Paul, Minnesota.
Recurrent Pseudomonas aeruginosa endophthalmitis after cataract surgery can be aggressive. Complete eradication may require intraocular lens and capsule removal, alongside vitrectomy and antibiotics.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Endophthalmitis is a serious intraocular infection.
- Pseudomonas aeruginosa is a particularly virulent pathogen in endophthalmitis cases.
Purpose of the Study:
- To describe a case of recurrent endophthalmitis caused by Pseudomonas aeruginosa.
- To highlight the management challenges and treatment outcomes.
Main Methods:
- Case evaluation for presumed endophthalmitis post-cataract surgery.
- Management involved pars plana vitrectomy and intravitreal antibiotics.
- Surgical intervention included intraocular lens and lens capsule removal.
Main Results:
- Successful resolution of Pseudomonas aeruginosa intraocular infection was achieved.
- Multiple pars plana vitrectomies were required.
- Final visual acuity improved to 20/30 after explantation.
Conclusions:
- Pseudomonas aeruginosa can cause aggressive, fulminant endophthalmitis.
- Intraocular lens and lens capsule removal may be necessary for complete eradication.
- Prompt and aggressive management is crucial for visual recovery.
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