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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Bilateral simultaneous endogenous Aspergillus endophthalmitis in an immunocompetent patient
Nishant Sachdev1, Pawan Gupta, Ramandeep Singh
1From the Departments of *Ophthalmology and †Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Purpose:
To report a case of bilateral endogenous Aspergillus endophthalmitis in an immunocompetent patient.
Methods:
We report a young immunocompetent 26-year-old Indian woman who presented with bilateral simultaneous endogenous endophthalmitis and was managed with pars plana vitreous surgery in both the eyes.
Results:
Smear examination of the vitrectomy specimen from the left eye identified septate hyphae with acute-angle branching, which on culture showed growth of Aspergillus fumigatus. A detailed systemic evaluation failed to reveal any systemic focus or predisposing factor for fungal infection. The patient had received an intravenous dextrose infusion 2 weeks before this episode while being treated at a rural hospital for malarial infection. During follow-up, she developed bilateral rhegmatogenous retinal detachment requiring revised pars plana vitreous surgery with silicon oil tamponade.
Conclusion:
An immunocompetent patient can present with bilateral simultaneous endogenous Aspergillus endophthalmitis after receiving an intravenous infusion of presumably contaminated dextrose solution.
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