Related Experiment Video
Updated: Apr 21, 2026

Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards
Published on: September 3, 2020
Central serous chorioretinopathy associated with narcolepsy
Joan T Kim1, Philip S Eichling, Mingwu Wang
1From the *Department of Ophthalmology and Vision Science, University of Arizona, Tucson, Arizona; and †Comprehensive Sleep Solutions, Tucson, Arizona.
Purpose:
The purpose of this study was to describe a case of central serous chorioretinopathy (CSC) associated with narcolepsy.
Methods:
Case report.
Results:
A 34-year-old man was followed for persistent CSC in his left eye for more than 11 months. He did not have any known risk factors for CSC, including obstructive sleep apnea. However, he experienced disrupted sleep because of narcolepsy, which was inadequately treated. After 2 weeks of adequate treatment for his narcolepsy, fundus examination and optic coherence tomography demonstrated complete resolution of his CSC.
Conclusion:
As this case report suggests, overactivation of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system, seen with disrupted and poor quality sleep, may contribute to the development of CSC. Risk factors for CSC should include sleep disorders that can lead to chronic sleep deprivation.
Related Concept Videos
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Narcolepsy
Photoreceptors and Visual Pathways
REM Sleep Behavior Disorder
RBD is significantly associated with...
Nephrotic Syndrome I : Introduction
Cushing Syndrome II: Pathophysiology

