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Updated: Apr 21, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Bacillus licheniformis as a cause of delayed-onset recurrent pseudophakic endophthalmitis-a rare case report
Tapas Ranjan Padhi1, Savitri Sharma, Sujata Das
1From the *Retina and Vitreous Service; †Ocular Microbiology Service; and ‡Cornea & Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Orissa, India.
Purpose:
To report a case of delayed-onset recurrent pseudophakic endophthalmitis caused by Bacillus licheniformis.
Method:
Retrospective review of a case.
Results:
A 30-year-old lady (s/p pseudophakia 10 years) presented with features of acute endophthalmitis and a vision of light perception in the left eye. She had received 15 intravitreal injections and systemic corticosteroids earlier for similar complaints. A core vitrectomy and intravitreal antibiotics injection improved her vision to 20/70, although the symptoms recurred a week later. Intraocular lens explantation with a repeat vitrectomy and intravitreal antibiotics was performed. The vitreous/aqueous fluid on both occasions grew B. licheniformis sensitive to fluoroquinolones, vancomycin, and gentamicin. One year after the second surgery, her vision was 20/30 with a quiet eye.
Conclusion:
This case shows that delayed-onset recurrent endophthalmitis after cataract extraction may be caused by Bacillus spp. and, despite sensitivity to most antibiotics, may require intraocular lens explantation for eradication of the infection.
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