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Updated: Apr 21, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Relationship between cranial mechanics and dysmorphic dentofacial characteristics: a cross-sectional study
Sophie Fournier-Bourgier1, Romain Fournier, Martin Garet
1Research Department CIDO (Centre International d'Ostéopathie) , Saint-Etienne, France.
Osteopathic assessment of cranial movement correlates with orthodontic diagnoses of sagittal dysmorphologies. Cranial flexion relates to skeletal class III, while extension relates to skeletal class II.
Area of Science:
- Osteopathy
- Orthodontics
- Craniofacial Development
Background:
- Cranial dysfunctions assessed by osteopaths may relate to dentofacial characteristics.
- Cephalometric analysis is used by orthodontists to diagnose sagittal dysmorphologies.
Purpose of the Study:
- To evaluate the correlation between osteopathically detected cranial dysfunctions and orthodontically diagnosed sagittal dysmorphologies.
- To investigate the relationship between cranial bone mobility and skeletal classes.
Main Methods:
- 106 children (6-12 years) were assessed by an osteopath for cranial movement (flexion/extension).
- Reproducibility was tested on 27 subjects.
- Cephalometric analysis determined sagittal dysmorphologies and spheno-occipital synchondrosis (SOS) angle.
Main Results:
- Osteopaths found more cranial movement in extension for skeletal class II patients.
- More cranial movement in flexion was found in skeletal class III patients.
- No significant difference in SOS angulation was observed across skeletal classes.
Conclusions:
- The study supports a correlation between cranial vault bone mobility and sagittal dentofacial characteristics.
- Developmental anomalies may lead to cranial flexion (skeletal class III) or extension (skeletal class II).
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