Related Experiment Video
Updated: Apr 21, 2026
Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
Published on: March 11, 2016
Fundus autofluorescence in retinopathy caused by deferoxamine toxicity
Shantan Reddy1, Diana Iturralde, Catherine Meyerle
1From the *Department of Ophthalmology, Manhattan Eye, Ear & Throat Hospital and New York University School of Medicine, New York, New York; and †Vitreous-Retina-Macula Consultants of New York, New York, New York.
Purpose:
To describe the fundus autofluorescence photographic pattern in a case of deferoxamine retinopathy.
Methods:
Observational case report.
Results:
A 91-year-old woman receiving intravenous deferoxamine treatment presented with a history of deteriorating vision in both eyes. Autofluorescence photography revealed well circumscribed areas of hyperautofluorescence that correlated with areas of pigmentation shown by color photography. Deferoxamine retinopathy was diagnosed.
Conclusion:
Fundus autofluorescence photography is a noninvasive imaging method for early detection of deferoxamine retinopathy and can be used to monitor the status of the macula in patients at risk for this toxicity.
