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Updated: Apr 21, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Early spontaneous closure after reopening of a previously repaired macular hole
Kaveh Vahdani1, Jonathan C Park, Vasant S Raman
1The Royal Eye Infirmary, Plymouth, United Kingdom.
Purpose:
To describe a case of early spontaneous closure of macular hole after reopening after previous successful surgical repair.
Methods:
A 72-year-old female patient was treated for stage 2 idiopathic macular hole in the right eye. The hole remained anatomically closed for 2 months postoperatively, before reopening 1 month later.
Results:
The patient was listed for revision surgery; however, on the day of the operation, which was 2 months after the reopening, the hole seemed to have closed spontaneously. Two years later, the macular hole remains closed with best-corrected visual acuity of 6/9.
Conclusion:
Spontaneous closure of macular holes after reopening is a rare phenomenon. The case presented here demonstrates that for early reopening of macular holes, a period of observation with serial optical coherence tomography may allow the hole to close spontaneously before proceeding with further surgical intervention.

