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Acute unilateral toxoplasma retinochoroiditis associated with adalimumab, a tumor necrosis factor-α antagonist
Alaa Radwan1, Ujwala Baheti, Cheryl A Arcinue
1Massachusetts Eye Research and Surgery Institution, Cambridge, Massachusetts.
Purpose:
The purpose of this study was to report a case of a patient with unilateral toxoplasma retinochoroiditis while on treatment with adalimumab, an anti-tumor necrosis factor α agent for ulcerative colitis.
Methods:
This is a descriptive case report.
Results And Discussion:
In addition to the patient with toxoplasma retinochoroiditis, there is one published report of two patients who developed toxoplasma chorioretinitis while on anti-tumor necrosis factor α therapy for rheumatoid arthritis: one was on adalimumab and methotrexate and the other one was on etanercept and methotrexate.
Conclusion:
The authors need to be aware of this potentially vision threatening risk with anti-tumor necrosis factor α therapy.
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