Polypoidal choroidal vasculopathy in association with choroidal nevus
Enrico Peiretti1, Maria C Pozzoni, Maurizio Fossarello
1From the *Vitreous Retina Macula Consultants of New York, the LuEsther T. Merz Retina Research Laboratory, Manhattan Eye Ear and Throat Hospital, New York; and †Department of Surgical Sciences, Eye Clinic, University of Cagliari, Italy.
Retinal Cases & Brief Reports
|November 13, 2014
Summary
Polypoidal choroidal vasculopathy (PCV)-like changes can occur with choroidal nevus. Indocyanine green angiography (ICG) helps identify these neovascularizations in patients with choroidal nevus.
Area of Science:
- Ophthalmology
- Medical Imaging
- Vascular Biology
Background:
- Choroidal nevus is a common benign lesion of the uvea.
- Polypoidal choroidal vasculopathy (PCV) is a subtype of neovascular age-related macular degeneration.
- The association between choroidal nevus and PCV is not well-established.
Purpose of the Study:
- To investigate the potential association between choroidal nevus and polypoidal choroidal vasculopathy (PCV).
- To describe clinical findings in patients presenting with both conditions.
Main Methods:
- Case report of two patients with subretinal exudation and choroidal nevus.
- Comprehensive ophthalmologic examination including slit-lamp biomicroscopy.
- Diagnostic imaging: color fundus photography, fluorescein angiography (FA), and indocyanine green angiography (ICG).
Main Results:
- ICG angiography revealed choroidal neovascularization with PCV-like characteristics in both eyes of the two patients.
- Subretinal exudation was a presenting sign in these cases.
- FA showed findings suggestive of neovascularization, but ICG provided definitive characterization.
Conclusions:
- PCV-like vascular changes can be associated with choroidal nevus.
- ICG angiography is crucial for differentiating PCV-like neovascularization in the context of choroidal nevus.
- This association highlights the importance of advanced imaging in evaluating atypical presentations of choroidal lesions.
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