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Updated: Apr 21, 2026

Dissection of Human Vitreous Body Elements for Proteomic Analysis
Published on: January 23, 2011
Histologic and immunohistochemical features of a vitreous cyst
P Kumar Rao1, Arghavan Almony, Gaurav K Shah
1From the *Department of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis; †Barnes Retina Institute, St. Louis, MO; and ‡University of Kansas Hospital, Kansas City.
Purpose:
To report the histologic and immunohistochemical features of a congenital vitreous cyst.
Methods:
Interventional case report with immunohistochemical correlation. A 58-year-old woman with known vitreous cyst since childhood had an enlarging visual floater. The vitreous cyst was removed by pars plana vitrectomy and central vision was restored.
Results:
Pathology confirmed a vitreous cyst derived from neural and glial tissue and consistent with retinal origin.
Conclusions:
Congenital vitreous cysts, derived from neural and glial tissue, can be safely removed using pars plana vitrectomy.

