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Updated: Apr 21, 2026

Dissection of Human Vitreous Body Elements for Proteomic Analysis
Published on: January 23, 2011
Wandering nematode in the vitreous cavity
Samir Mohamed El-Baha1, Tarek Samir Hemeida, Helmy Tewfik Omar
1From the *Department of Ophthalmology, Alexandria University; †Armed Forces Hospitals; ‡General Ophthalmology Hospital, Alexandria; and §Department of Parasitology, High Health Institute, Alexandria, Egypt.
Background:
Bancroftian filariasis is focally endemic in Egypt. There have been many reports of intraocular filariasis; the question of why one filarial nematode should cause ocular disease while another does not may be related to the behavior of the microfilaria and the location of the cross-reacting ocular antigen.
Methods:
A 35-year-old woman with a white worm approximately 3 disk diameters in length penetrating the left macula, moving in the vitreous cavity, with a part of its length in the vitreous cavity while the rest was embedded subretinally, is described. Pars plana vitrectomy was performed and the worm was aspirated successfully.
Results:
Parasitologic study of the aspirated worm identified juvenile Wuchereria bancrofti. Ivermectin 150 μg/kg was given orally to the patient after identification of the worm. Six weeks later, the patient's visual acuity had improved to 20/200.
Conclusion:
Intravitreal parasites should be surgically removed as soon as possible.
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