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Chronic postoperative fungal endophthalmitis caused by trichosporon asahii

Ronald W Slocumb1, Susan G Elner, Edward F Hall

  • 1From the Department of Ophthalmology and Visual Sciences, University of Michigan, Kellogg Eye Center, Ann Arbor, Michigan.

Retinal Cases & Brief Reports
|November 13, 2014
PubMed
Abstract

Insights

This case report details a rare instance of chronic fungal endophthalmitis caused by Trichosporon asahii following cataract surgery. The patient achieved successful treatment with antifungal medication and surgical intervention without requiring intraocular lens removal.

Area of Science:

  • Ophthalmology
  • Mycology
  • Infectious Diseases

Background:

  • Fungal endophthalmitis is a serious intraocular infection that can occur postoperatively.
  • Chronic forms of fungal endophthalmitis are less common and can present diagnostic challenges.
  • Trichosporon species are emerging as opportunistic pathogens in ocular infections.

Purpose of the Study:

  • To report the first case of chronic postoperative fungal endophthalmitis caused by Trichosporon asahii.
  • To describe the clinical presentation and management of this rare condition.

Main Methods:

  • Retrospective case report.
  • Culture-proven diagnosis of Trichosporon asahii endophthalmitis.
  • Description of treatment including pars plana vitrectomy, capsulectomy, and oral voriconazole.

Main Results:

  • An 82-year-old woman developed chronic fungal endophthalmitis 18 months after uneventful phacoemulsification and intraocular lens implantation.
  • Culture confirmed Trichosporon asahii as the causative agent.
  • Successful treatment was achieved with pars plana vitrectomy, capsulectomy, and oral voriconazole, preserving the intraocular lens.

Conclusions:

  • This is the first documented case of chronic postoperative endophthalmitis due to Trichosporon asahii.
  • Successful management can be achieved with a combination of surgical intervention and systemic antifungal therapy, potentially avoiding intraocular lens explantation.

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