Related Experiment Video
Updated: Apr 21, 2026

Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Postsurgical sympathetic ophthalmia refractory to treatment: the response to infliximab
Emilio Dorronzoro Ramírez1, Juan Jacobo Guijarro González, Rosario García Vicuña
1*Uveitis Department †Rheumatology Department, Hospital Universitario de La Princesa, Madrid, Spain.
Purpose:
A clinical case of a postoperative sympathetic ophthalmia is presented and its response to the monoclonal antibody infliximab.
Patients:
A 61-year-old woman.
Results:
The treatment with prednisone, cyclosporine, azathioprine, and mycophenolate mofetil did not completely control the loss of visual acuity caused by the disease. Monthly intravenous infusions of infliximab (5 mg/kg) significantly improved the condition of the patient, allowing the cyclosporine and azathioprine to be withdrawn and the prednisone to be reduced to 10 mg/d.
Conclusion:
The use of the immunosuppressive drug infliximab in combination with prednisone improved the prognosis of a patient suffering from sympathetic ophthalmia. The reported effectiveness of infliximab in the treatment of T lymphocyte-mediated diseases suggests that it could be used earlier in cases of sympathetic ophthalmia when treatment with corticosteroids must be shortened.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Ophthalmic Drug Delivery Systems
Glaucoma: Overview

