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[Management of multiresistant pathogens in urology]
G Magistro1, C Gratzke, C G Stief
1Urologische Klinik und Poliklinik, Klinikum der Ludwig-Maximilians-Universität - Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland, Giuseppe.Magistro@med.uni-muenchen.de.
Der Urologe. Ausg. A
|November 14, 2014
Summary
Antimicrobial resistance in gram-negative bacteria, especially Enterobacteriaceae, is a growing global health threat. New definitions for multidrug-resistance are needed to guide hygiene measures against these challenging pathogens.
Area of Science:
- Public Health
- Infectious Diseases
- Microbiology
Context:
- Rising antimicrobial resistance (AMR) affects both gram-positive and gram-negative bacteria.
- Increasing resistance to third-generation cephalosporins and carbapenems in Enterobacteriaceae is a significant concern.
- Multidrug-resistant pathogens pose a substantial socioeconomic burden due to morbidity, mortality, and healthcare costs.
Purpose:
- To address the growing public health issue of multidrug-resistant pathogens.
- To develop updated definitions for multidrug-resistance.
- To inform the creation of effective hygiene measures for infections and colonization by multidrug-resistant gram-negative bacilli.
Summary:
- Epidemiological data highlights the escalating problem of antimicrobial resistance, particularly in gram-negative bacteria like Enterobacteriaceae.
- Resistance to key antibiotics such as third-generation cephalosporins and carbapenems is increasing.
- The Commission for Hospital Hygiene and Infection Prevention (KRINKO) aims to establish new definitions for multidrug-resistance.
Impact:
- Facilitates the development of targeted hygiene strategies for preventing and controlling infections caused by multidrug-resistant gram-negative bacilli.
- Aims to mitigate the significant morbidity, mortality, and economic impact associated with these resistant pathogens.
- Contributes to enhanced hospital hygiene and infection prevention protocols worldwide.
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