The second five years of sequential injection chromatography: significant developments in the technology and...

Area of Science:

• Analytical Chemistry
• Separation Science

Background:

• Sequential injection chromatography (SIC) emerged in 2003 as an advancement in flow injection analysis.
• It offers advantages like simplicity, speed, reagent economy, and reduced environmental impact compared to traditional methods.
• Initial applications were predominantly in pharmaceutical analysis, facing some technical challenges.

Purpose of the Study:

• To review recent developments in sequential injection chromatography between 2008 and 2013.
• To analyze how these advancements enhance SIC efficiency and broaden its applicability.
• To discuss methodologies, controlling conditions, and analytical outcomes reported during this period.

Main Methods:

• Review of scientific literature published between 2008 and 2013 focusing on sequential injection chromatography.
• Analysis of reported technological developments and their impact on analytical performance.
• Examination of specific SIC methodologies, operational parameters, and achieved results.

Main Results:

• Significant technological developments in SIC occurred between 2008 and 2013.
• These advancements improved the efficiency and broadened the application scope of SIC.
• SIC applications expanded to include biological, food, and environmental analyses, alongside its established pharmaceutical use.

Conclusions:

• Sequential injection chromatography has evolved considerably, overcoming initial limitations.
• Recent developments have enhanced its analytical capabilities and versatility.
• SIC is a valuable and increasingly applicable technique across diverse scientific fields.