Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cell Specific Gene Expression

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Accuracy of menu calorie labelling in the England out-of-home food sector during 2024: assessment of a national food policy.

The British journal of nutrition·2025

Same author

An Ecological Momentary Assessment Study of Fluctuations in Inhibitory Control and Its Predictive Validity of Alcohol Use.

Substance use & misuse·2025

Same author

Comparing the impact of feedback on excess calories and physical activity calorie equivalent (PACE) information on consumer behaviour in an online hypothetical restaurant setting.

Appetite·2025

Same author

Elucidating tissue and subcellular specificity of the entire SUMO network reveals how stress responses are fine-tuned in a eukaryote.

Science advances·2025

Same author

Social influence increases the value and consumption of alcohol in the laboratory.

Alcohol, clinical & experimental research·2025

Same author

Cities Are Concentrators of Complex, MultiSectoral Interactions Within the Human-Earth System.

Earth's future·2025

Search research articles

Related Experiment Video

Updated: Apr 21, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Changes in CEBPB expression in circulating leukocytes following eccentric elbow-flexion exercise.

Jamie Blackwell¹, Lorna W Harries, Luke C Pilling

¹Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, St. Luke's Campus, Exeter, UK.

The Journal of Physiological Sciences : JPS

|November 14, 2014

Summary

CCAAT enhancer-binding protein beta (CEBPB) levels in blood increase following exercise-induced muscle damage in humans. This finding supports CEBPB

More Related Videos

Combining Multiple Data Acquisition Systems to Study Corticospinal Output and Multi-segment Biomechanics

Combining Multiple Data Acquisition Systems to Study Corticospinal Output and Multi-segment Biomechanics

Published on: January 9, 2016

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

Related Experiment Videos

Last Updated: Apr 21, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Combining Multiple Data Acquisition Systems to Study Corticospinal Output and Multi-segment Biomechanics

Combining Multiple Data Acquisition Systems to Study Corticospinal Output and Multi-segment Biomechanics

Published on: January 9, 2016

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

Area of Science:

Exercise Physiology
Molecular Biology
Muscle Regeneration

Background:

CCAAT enhancer-binding protein beta (CEBPB) is crucial for M2 macrophage-mediated muscle regeneration in mice.
In humans, CEBPB blood expression correlates strongly with muscle strength.

Purpose of the Study:

To investigate if CEBPB blood expression increases 2 days post-exercise in humans after muscle damage and repair.
To explore the relationship between exercise-induced muscle damage and CEBPB expression.

Main Methods:

Sixteen healthy males performed damaging elbow flexor exercises.
Blood samples were collected pre- and post-exercise (days 1, 2, 4, 7).
CEBPB gene expression analyzed via qRT-PCR; muscle damage assessed by torque and creatine kinase (CK).

Main Results:

In subjects with high CK levels (>10,000 U/l), CEBPB expression significantly increased from baseline to 2 days post-exercise (p=0.006).
Muscle-damaging exercise induced CEBPB transcript expression in peripheral blood.
No significant changes observed in related gene expression or selected cytokines.

Conclusions:

Exercise-induced muscle damage in humans can lead to increased CEBPB transcript expression in peripheral blood.
The observed association between blood CEBPB levels and muscle strength may reflect CEBPB's role in muscle repair processes.