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Updated: Apr 21, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
[A case of lymphoepithelioma-like carcinoma of the bladder]
Toshio Fujino1, Masashi Kubota1, Ryuichi Nishiyama1
1The Department of Urology, Ijinkai Takeda General Hospital.
Abstract:
Lymphoepithelioma-like carcinoma (LELC) of the bladder is very rare and only a few cases have been reported so far. Here, we report a case of LELC of the bladder with distant metastasis. A 73-year-old man presented with macroscopic hematuria and miction pain. Cystoscopy revealed non-papillary tumor and tissue biopsy was performed. Histopathological examination showed pure type of LELC in the bladder. Fludeoxyglucose positron emission tomography revealed lymph node metastasis. The tumor progressed rapidly and the patient died 4 months later. Although the prognosis of pure type of LELC has been reported to be good, our case indicates that the prognosis of pure type with distant metastasis may be poor.
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