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Updated: Apr 21, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Indications, implications and applications of renal denervation. Have we discovered something new?
Cristiano de Oliveira Dietrich, Fabio Martins Nardo Botelho, Erlon Oliveira de Abreu-Silva1
1Sao Paulo Hospital, Federal Unversity of Sao Paulo, 715 Napoleao de Barros St, Sao Paulo, Zipe Code 04024-002, Sao Paulo, Brazil. codietrich@gmail.com.
Abstract:
Hyperactivity of sympathetic nervous system is one of the main mechanisms to play a role in the pathophysiology of hypertension. Its high prevalence and the low rates of adequate blood pressure control with pharmacological treatment brought interest to novel therapeutical strategies. Percutaneous renal sympathetic denervation emerged as an effective and safe alternative to reduce blood pressure in patients with resistant hypertension. Other potential indications to this procedure are heart failure, cases of insulin resistance, obesity, obstructive sleep apnea and cardiac arrhythmias.
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