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Characterization of rearranged Y chromosomes in human testicular tumor cell lines
J Arnemann1, G Gradl, J Casper
1Institut für Humangenetik, Universitätskliniken, Göttingen, West Germany.
Cancer Genetics and Cytogenetics
|February 1, 1989
Abstract:
Cytogenetic analysis of four cell lines established from two different human testicular tumors revealed rearranged or missing Y chromosomes. Southern blot analysis and in situ hybridization with different Y-derived human DNA sequences revealed the existence of Y chromosomal material even in a line without a cytogenetically visible Y chromosome and clarified the composition of Y marker chromosomes.