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Updated: Apr 21, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
Efficient synthesis of aza-triquinacene derivatives via cycloaddition of 2,6-diazasemibullvalenes with nitroso
Ming Zhan1, Shaoguang Zhang, Zhe Huang
1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871 (China), Fax: (+86) 10-6275-1708.
Abstract:
The reaction between 2,6-diazasemibullvalenes and nitroso compounds was investigated. Aza-triquinacene derivatives of interesting structural and synthetic chemistry were generated highly selectively in good to excellent isolated yields. This reaction, which was rarely found between common aziridine derivatives and nitroso compounds, could be attributed to the rigid polycyclic ring system and the substitution patterns of 2,6-diazasemibullvalenes. Δ(1) -Bipyrroline derivatives were formed in excellent yields when these aza-triquinacene derivatives were treated with SmI2 .
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