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High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
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Predictive value of interferon-lambda gene polymorphisms for treatment response in chronic hepatitis C

Simone Susser1, Eva Herrmann2, Christian Lange1

  • 1Medical Department 1, Goethe-University Hospital Frankfurt/Main, Frankfurt, Germany.

Plos One
|November 14, 2014
PubMed
Summary

Interferon-lambda (IFN-L4) and IL28B gene polymorphisms predict treatment success for chronic hepatitis C. Combining these genetic markers optimizes prediction of sustained virologic response (SVR) for personalized antiviral therapies.

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