Related Experiment Video
Updated: Apr 21, 2026

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice
Published on: January 24, 2025
Obesity, adipokines and cancer: an update
C H Lee1, Y C Woo1, Y Wang2,3,4
1Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, Hong Kong.
Abstract:
Obesity causes dysfunction of adipose tissue, with resultant chronic inflammation and adverse interplay of various adipokines, sex steroids and endocrine hormones. All these drive tumourigenesis and explain the epidemiological link between obesity and cancer. Over the past decade, the associations among obesity, adipokines and cancer have been increasingly recognized. Adipokines and their respective signalling pathways have drawn much research attention in the field of oncology and cancer therapeutics. This review will discuss the recent advances in the understanding of the association of several adipokines with common obesity-related cancers and the clinical therapeutic implications.
Related Concept Videos
Obesity
Psychoneuroimmunology: Diabetes and Cancer
Adaptive Mechanisms in Cancer Cells
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
mTOR Signaling and Cancer Progression
The mTOR pathway or the...
mTOR Signaling and Cancer Progression

