Related Experiment Video
Updated: Apr 21, 2026

Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
Foreign Body Granuloma Following Orbital Reconstruction with Porous Polyethylene
Peter J Timoney1, Jeremy D Clark, Paul A Frederick
1*Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington; †Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville; ‡Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky; and §Department of Ophthalmology, University of Kansas, Lawrence, Kansas, U.S.A.
Abstract:
Porous polyethylene is commonly used in the orbit for fracture repair and anophthalmic reconstruction; it reportedly has a good safety profile and integrates well into host tissue. Foreign body reaction to porous polyethylene has been reported in facial tissue, but to our knowledge, not in the orbit. The authors report 2 cases of foreign body inflammatory giant cell reaction in patients who underwent orbital fracture repairs with porous polyethylene implants.

