Medical intervention in parent-reported infant gastro-oesophageal reflux: A population-based study

Sun Hua1,2, Rachel L Peters1,3, Katrina J Allen1,4,5,3

  • 1Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria, Australia.

Insights

Approximately 14% of infants seek medical advice for gastro-oesophageal reflux (GOR) in their first year. Anti-reflux medication use is high, even for uncomplicated GOR, despite lacking evidence of effectiveness.

Area of Science:

  • Pediatrics
  • Gastroenterology
  • Public Health

Background:

  • Gastro-oesophageal reflux (GOR) is common in infants.
  • Understanding health-seeking behaviors and medical interventions for GOR is crucial for appropriate infant care.

Purpose of the Study:

  • To determine the incidence of gastro-oesophageal reflux (GOR) in infants within the first year of life.
  • To investigate health-seeking behaviors and medical interventions for infants experiencing GOR symptoms.

Main Methods:

  • The study utilized data from the longitudinal, population-based HealthNuts study.
  • Infant GOR symptoms, food allergy, and treatments were assessed via parental questionnaires at 12 months.
  • Logistic regression modeled factors associated with seeking healthcare for infant GOR.

Main Results:

  • Gastro-oesophageal reflux (GOR) was reported in 23% of 4674 infants, with 64% consulting a medical practitioner.
  • Factors influencing medical consultation included prematurity and family history of atopy.
  • Anti-reflux medication was used by 8% of infants, and 6% changed formula, with parental perception of infant distress and symptom duration being key factors for seeking treatment.

Conclusions:

  • Around 14% of infants receive medical advice for gastro-oesophageal reflux (GOR) symptoms annually.
  • The widespread use of anti-reflux medication for uncomplicated GOR persists, despite limited evidence supporting its efficacy.
  • Further research is needed to guide appropriate management strategies for infant GOR.
Abstract

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