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Updated: Apr 21, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Myocardial performance is impaired in patients with branch retinal vein occlusion
Berkant Kaderli1, Aysel Aydin Kaderli2, Sumeyye Gullulu3
1Department of Ophthalmology, Faculty of Medicine, Uludag University, Bursa, Turkey.
Objective:
To investigate whether the Tei index, which is an indicator of global myocardial function and an independent predictor of cardiac death, is increased in patients with branch retinal vein occlusion (BRVO).
Methods:
The Tei index was used to evaluate myocardial performance, in addition to conventional echocardiographic evaluation of myocardial structural and functional changes, in patients with BRVO, patients with hypertension and healthy controls.
Results:
Out of 36 patients with BRVO (18 female, 18 male; 17 hypertensive, 19 normotensive), 29 patients with hypertension (15 female, 14 male) and 28 healthy controls (15 female, 13 male), there were no significant between-group differences in age and sex. The mitral A wave was higher and mitral E/A ratio, mitral E wave and ejection time were lower, in patients with BRVO than in healthy controls. Mean Tei index was significantly higher in the BRVO group than in patients with hypertension or healthy controls. Compared with healthy controls, the Tei index was significantly higher in hypertensive and normotensive patients with BRVO.
Conclusion:
Myocardial performance is decreased in patients with BRVO, independent of whether or not they have hypertension.
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