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Chronic neonatal coxsackie myocarditis
1Department of Neonatology, Shaare Zedek Medical Center, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Archives of Disease in Childhood
|March 1, 1989
Summary
A newborn developed severe myocarditis and permanent myocardial calcification due to Coxsackie virus B1 infection. This infant
Area of Science:
- Neonatal cardiology
- Pediatric infectious diseases
- Viral myocarditis
Background:
- Neonatal myocarditis is a serious condition.
- Coxsackie B viruses are a common cause of viral infections in neonates.
- Myocardial calcification can occur in severe cases.
Observation:
- A baby girl with a birth weight of 2540 g developed myocarditis.
- Gross, permanent myocardial calcification was observed.
- The infant's clinical course was progressively downhill, leading to death at 14 months of age.
Findings:
- Neutralizing antibody titers to Coxsackie virus group B1 rose significantly.
- The patient exhibited a protracted disease course.
- This case represents a novel clinical presentation of fatal neonatal Coxsackie B virus infection.
Implications:
- This case highlights a new clinical form of fatal neonatal Coxsackie B virus infection.
- Understanding this protracted course is crucial for diagnosis and management.
- Further research into the pathogenesis of neonatal Coxsackie B virus infection is warranted.