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Updated: Apr 20, 2026

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
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Molecular patterns in human ulcerative colitis and correlation with response to infliximab

Brendan Halloran1, Jessica Chang, David Q Shih

  • 1*Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, AB, Canada; †F. Widjaja Foundation, Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; ‡Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada; §Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; and ‖Division of Nephrology and Transplant Immunology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.

Inflammatory Bowel Diseases
|November 15, 2014
PubMed
Summary

Ulcerative colitis (UC) molecular profiles resemble transplant rejection, showing gene expression changes that correlate with disease severity and predict infliximab treatment response. This molecular signature offers insights into therapeutic outcomes.

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