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DUSP4 regulates neuronal differentiation and calcium homeostasis by modulating ERK1/2 phosphorylation

Sun Young Kim1, Yong-Mahn Han, Mihee Oh

  • 11 Department of Biological Sciences, Center for Stem Cell Differentiation, KAIST , Daejeon, Republic of Korea.

Stem Cells and Development
|November 15, 2014
PubMed
Summary

Dual specificity phosphatase 4 (DUSP4) is essential for neuronal differentiation and neurogenesis in embryonic stem cells (ESCs). DUSP4 regulates the extracellular signal-regulated kinase (ERK) and calcium signaling pathways critical for neuron development.

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