The skin and HIV: no superficial matter

Area of Science:

• Dermatology
• Infectious Diseases
• Immunology

Background:

• The majority of patients with human immunodeficiency virus (HIV) develop skin disorders.
• These conditions are often categorized as infectious, neoplastic, or inflammatory.
• Pruritus (itch) is common and can significantly impact quality of life.

Purpose of the Study:

• To review the spectrum of skin disorders in HIV-infected patients.
• To discuss therapeutic strategies for inflammatory skin conditions and pruritus.
• To highlight the evolving understanding and treatment of psoriasis in the context of HIV.

Main Methods:

• Literature review and synthesis of current knowledge on HIV-associated dermatoses.
• Discussion of therapeutic options including antiretroviral therapy, topical agents, and systemic medications.
• Emphasis on the role of topical corticosteroids and management of refractory itch.

Main Results:

• HIV-infected individuals frequently experience diverse skin conditions.
• Effective management strategies involve a combination of therapies tailored to the specific disorder.
• Psoriasis, while not more frequent, can be more severe in HIV patients, with new treatments emerging.

Conclusions:

• Comprehensive dermatological care is essential for HIV-infected patients.
• Management of skin disorders and pruritus can improve patient outcomes and quality of life.
• Advances in understanding and treating HIV-associated skin conditions, including psoriasis, are ongoing.