Probiotics and pregnancy

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Updated: Apr 20, 2026

Probiotic Studies in Neonatal Mice Using Gavage
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Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

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Luisa F Gomez Arango1, Helen L Barrett, Leonie K Callaway

  • 1School of Medicine, The University of Queensland, Butterfield Street, Herston, QLD, 4029, Australia, luisa.gomezarango@uq.net.au.

Current Diabetes Reports
|November 16, 2014
PubMed

Complications of pregnancy are associated with adverse outcomes for mother and baby in the short and long term. The gut microbiome has been identified as a key factor for maintaining health outside of pregnancy and could contribute to pregnancy complications. In addition, the vaginal and the recently revealed placental microbiome are altered in pregnancy and may play a role in pregnancy complications. Probiotic supplementation could help to regulate the unbalanced microflora composition observed in obesity and diabetes. Here, the impact of probiotic supplementation during pregnancy and infancy is reviewed. There are indications for a protective role in preeclampsia, gestational diabetes mellitus, vaginal infections, maternal and infant weight gain and allergic diseases. Large, well-designed randomised controlled clinical trials along with metagenomic analysis are needed to establish the role of probiotics in adverse pregnancy and infancy outcomes.

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