Related Experiment Video
Updated: Apr 20, 2026

Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses
Published on: May 2, 2019
Molecular evolution of kobuviruses in cats
Yoon-Young Cho1, Seong-In Lim, Yong Kwan Kim
1Animal and Plant Quarantine Agency, Anyang, Gyeonggi, 430-824, Republic of Korea.
Abstract:
Aichi virus, a causative agent of human gastroenteritis, is one of a number of animal viruses belonging to the genus Kobuvirus within the family Picornaviridae. The kobuvirus genome encodes several structural and nonstructural proteins; the capsid proteins encoded by the VP1 gene are key immunogenic factors. Here, we used the VP1 region to determine substitution rates and the time to the most recent common ancestor (TMRCA) by comparing feline kobuvirus (FKoVs) sequences with kobuvirus sequences isolated from members of other species. The substitution rate for FKoVs was 1.29 × 10(-2 )substitutions/site/year (s/s/y) and the TMRCA was 5.3 years.
Related Concept Videos
Viral Mutations
Retroviruses
Evolution of Microbial Genome
Retrovirus Life Cycles
Viruses with RNA Genomes
Human Virome

